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Intermediate Technical IVT

HDL-C

Also written as: HDL-C — high-density lipoprotein cholesterol

High-density lipoprotein cholesterol, often called 'good cholesterol' due to its protective cardiovascular effects.

Full Definition

High-density lipoprotein cholesterol (HDL-C) is a measure of cholesterol carried by high-density lipoproteins in the blood. HDL particles transport cholesterol from peripheral tissues back to the liver for disposal, a process known as reverse cholesterol transport. Higher HDL-C levels are generally associated with lower cardiovascular risk, though recent studies have questioned whether raising HDL-C therapeutically provides cardiovascular benefits. Normal HDL-C levels are considered above 40 mg/dL in men and above 50 mg/dL in women.

Usage

Usage note: Always hyphenate. Use HDL-C rather than HDL when referring specifically to cholesterol content.

In Context

  • "The patient's HDL-C level of 65 mg/dL was considered protective." — Laboratory report
  • "Low HDL-C remains an independent risk factor despite optimal LDL-C control." — Risk assessment note

Also known as

high-density lipoprotein cholesterol good cholesterol

Contrasted with

LDL-C

Don't confuse with

LDL-C total cholesterol

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