DES
Also written as: DES — Drug-Eluting Stent
Drug-eluting stent with antiproliferative coating to prevent restenosis.
Full Definition
A drug-eluting stent (DES) is a coronary stent coated with antiproliferative medications designed to prevent in-stent restenosis by inhibiting smooth muscle cell proliferation and neointimal hyperplasia. Modern DES utilize biocompatible or biodegradable polymers to deliver drugs such as everolimus, zotarolimus, or sirolimus in a controlled manner over several months. DES have largely replaced bare metal stents due to significantly lower rates of target lesion revascularization, though they require prolonged dual antiplatelet therapy.
Usage
Usage note: Distinguish from BMS (bare metal stent) in procedural documentation.
In Context
- "A second-generation DES was deployed with excellent angiographic result." — Procedure note
- "The patient remained on dual antiplatelet therapy 12 months post-DES implantation." — Follow-up note