FFR
Also written as: FFR — Fractional Flow Reserve
Fractional flow reserve, a physiological assessment of coronary stenosis severity using pressure wire measurements during maximal hyperemia.
Full Definition
Fractional flow reserve (FFR) is a lesion-specific index of coronary stenosis severity that represents the ratio of maximal achievable blood flow in a stenotic artery to the theoretical maximal flow in the same artery if it were normal. FFR is calculated as the ratio of distal coronary pressure to aortic pressure during maximal hyperemia, typically induced with adenosine. An FFR value ≤0.80 indicates hemodynamically significant stenosis that would benefit from revascularization, while values >0.80 suggest that medical therapy may be appropriate. This physiological assessment tool has revolutionized coronary intervention decision-making by providing functional rather than purely anatomical information about coronary lesions.
Usage
Usage note: Should always include the numeric value and interpretation regarding the 0.80 threshold for intervention.
In Context
- "FFR measurement of the intermediate lesion revealed a value of 0.75, indicating hemodynamic significance." — Physiological assessment report
- "Despite angiographic severity, the FFR was 0.85, supporting medical management over intervention." — Clinical decision documentation