Advanced
Technical
In the Industry Vocabulary Test
fractional flow reserve
Physiological measurement assessing functional significance of coronary stenosis during catheterization.
Full Definition
Fractional flow reserve (FFR) is a lesion-specific index of functional stenosis severity that represents the maximal achievable blood flow in a stenotic vessel as a fraction of the theoretical maximum flow in the same vessel if it were normal. The measurement is obtained using a pressure-sensitive guidewire during maximal hyperemia, typically induced by adenosine. An FFR value ≤0.80 indicates hemodynamically significant stenosis requiring revascularization.
Usage
Usage note: Commonly abbreviated as FFR in clinical documentation.
In Context
- "Fractional flow reserve measurement of 0.75 confirmed hemodynamic significance of the mid-LAD lesion." — Catheterization report
- "FFR-guided PCI resulted in improved clinical outcomes compared to angiography-guided intervention." — Research manuscript
Also known as
FFR
Don't confuse with
coronary flow reserve
instantaneous wave-free ratio