restenosis
Pronunciation: ree-steh-NO-sis
Re-narrowing of previously treated vessel segment, typically occurring within 6-12 months.
Full Definition
Restenosis is the pathological re-narrowing of a coronary artery segment that was previously treated with percutaneous intervention, most commonly occurring within 6-12 months post-procedure. The mechanism involves neointimal hyperplasia, smooth muscle cell proliferation, and vascular remodeling at the treatment site. Binary restenosis is defined as >50% diameter stenosis at follow-up angiography. Drug-eluting stents have significantly reduced restenosis rates compared to balloon angioplasty alone or bare metal stents, though late stent thrombosis remains a concern.
Usage
Usage note: Hyphenated form 're-stenosis' is also acceptable but less common.
In Context
- "Follow-up angiography at 8 months revealed significant in-stent restenosis." — Follow-up report
- "The patient underwent target lesion revascularization for focal restenosis." — Repeat procedure note