plegia solution
Cardioplegic solution used to induce cardiac arrest and protect the myocardium during cardiac surgery.
Full Definition
Plegia solution, short for cardioplegic solution, is a specialized fluid containing electrolytes and other protective agents designed to induce reversible cardiac arrest during surgery. The high potassium concentration causes membrane depolarization and cardiac standstill, while additives like blood, crystalloids, or specific substrates provide myocardial protection. Common formulations include St. Thomas', del Nido, and Buckberg solutions. The solution may be delivered antegrade through the aortic root or retrograde through the coronary sinus. Temperature (cold vs. warm) and composition vary based on surgical requirements and institutional protocols.
Usage
Usage note: Often shortened to 'plegia' in surgical documentation.
In Context
- "Cold blood plegia solution was administered antegrade every 20 minutes." — Perfusion record
- "The surgeon noted excellent cardiac arrest with the del Nido plegia solution." — Operative report