Rasmussen Encephalitis
Pronunciation: RAHZ-muh-sen en-sef-ah-LYE-tis
A rare chronic inflammatory brain disorder causing progressive focal seizures and unilateral brain atrophy.
Full Definition
Rasmussen encephalitis is a rare, chronic inflammatory disorder affecting one cerebral hemisphere, typically presenting in childhood with progressive focal seizures, hemiparesis, and cognitive decline. The condition is characterized by T-cell mediated inflammation leading to cortical atrophy and gliosis. Diagnosis relies on clinical criteria including focal seizures, unilateral cortical deficits, and MRI evidence of progressive hemispheric atrophy. Treatment is challenging and may include immunosuppressive therapy or hemispherectomy in severe cases.
Usage
Usage note: Named after Theodore Rasmussen; always capitalize the eponym.
In Context
- "The progressive hemiparesis and focal seizures raised suspicion for Rasmussen encephalitis." — Case presentation
- "Immunomodulatory therapy was initiated for suspected Rasmussen encephalitis." — Treatment plan