vagus nerve stimulation
Pronunciation: VAY-gus
Implantable device therapy that delivers electrical stimulation to the vagus nerve for treatment of medication-resistant epilepsy.
Full Definition
Vagus nerve stimulation (VNS) is a neuromodulation therapy involving surgical implantation of a device that delivers intermittent electrical stimulation to the left vagus nerve. The system consists of a pulse generator implanted in the chest and an electrode wrapped around the vagus nerve in the neck. VNS is approved for treatment of medication-resistant epilepsy in patients who are not candidates for resective surgery. The mechanism of action is not fully understood but may involve modulation of neurotransmitter systems and brain networks involved in seizure generation. Seizure reduction typically occurs gradually over months to years.
Usage
Usage note: Often abbreviated as VNS; specify left vagus nerve when detailed description needed.
In Context
- "Vagus nerve stimulation resulted in a 50% reduction in seizure frequency after one year." — Device clinic follow-up
- "The patient was evaluated for vagus nerve stimulation after exhausting medical therapies." — Neurosurgical consultation