oligodendroglioma
Pronunciation: oh-li-go-den-droh-gly-OH-mah
A type of primary brain tumor arising from oligodendrocytes, often characterized by calcifications and better prognosis than other gliomas.
Full Definition
Oligodendrogliomas are glial tumors that typically occur in the cerebral hemispheres, particularly the frontal and temporal lobes. They are characterized histologically by uniform cells with round nuclei and clear cytoplasm, often described as having a "fried egg" appearance. These tumors frequently contain calcifications visible on CT scans and may have better responses to chemotherapy than other gliomas. Molecular markers like 1p/19q codeletion influence prognosis and treatment decisions.
Usage
Usage note: Distinguish from other glioma types by molecular and histological characteristics.
In Context
- "The frontal lobe oligodendroglioma showed characteristic calcifications on CT imaging." — Radiology report
- "Molecular testing confirmed 1p/19q codeletion in the oligodendroglioma specimen." — Pathology report