Eisenmenger Syndrome
Pronunciation: EYE-zen-meng-er
A condition where pulmonary vascular disease develops from untreated left-to-right shunts, eventually reversing the direction of blood flow.
Full Definition
Eisenmenger Syndrome represents the irreversible end-stage of untreated congenital heart defects with initial left-to-right shunting. Over time, increased pulmonary blood flow leads to pulmonary vascular remodeling and severe pulmonary hypertension, eventually causing shunt reversal (right-to-left flow) and central cyanosis. This condition is considered inoperable for the original heart defect due to the established pulmonary vascular disease. Management focuses on symptom control and prevention of complications such as thromboembolism and sudden cardiac death.
Usage
Usage note: Named after Victor Eisenmenger. Note correct spelling with 'ei' not 'ie'. Distinguish from reversible pulmonary hypertension.
In Context
- "The patient developed Eisenmenger Syndrome secondary to an unrepaired ventricular septal defect." — Adult congenital heart disease clinic note
- "Eisenmenger Syndrome patients require specialized care and are not candidates for conventional cardiac surgery." — Treatment guideline document