Botulinum Toxin
Pronunciation: bot-yoo-LY-num TOK-sin
A neurotoxic protein derived from Clostridium botulinum, used in cosmetic dermatology to temporarily paralyse facial muscles and reduce the appearance of dynamic wrinkles.
Full Definition
Botulinum toxin is a neurotoxic protein produced by the bacterium Clostridium botulinum that blocks neuromuscular transmission by inhibiting acetylcholine release. In cosmetic dermatology, it is injected in minute, purified doses to relax overactive facial muscles responsible for dynamic wrinkles such as frown lines and crow's feet. Its effects are temporary, typically lasting three to six months, after which retreatment is required. Commercially available preparations include onabotulinumtoxinA (Botox), abobotulinumtoxinA (Dysport), and incobotulinumtoxinA (Xeomin). Editors should note that 'botulinum toxin' is the generic scientific term; brand names must be distinguished and capitalised accordingly.
Usage
Usage note: Do not use 'Botox' as a generic term; Botox is a registered trademark of Allergan. Use 'botulinum toxin' or the specific product name in clinical and regulatory copy.
In Context
- "The patient was treated with botulinum toxin injections to address glabellar lines and forehead creases." — Clinical case report
- "Editors must ensure that botulinum toxin is not conflated with dermal fillers in promotional medical copy." — Editorial style guide