Comedolytic
Pronunciation: koh-MEE-doh-LIT-ik
Describing an agent or treatment that breaks down or prevents the formation of comedones (clogged pores).
Full Definition
A comedolytic agent acts by loosening follicular plugs, dissolving the keratin and sebum matrix that forms comedones, or preventing their de novo formation. Common comedolytic ingredients include salicylic acid, retinoids, and azelaic acid. In editorial contexts, 'comedolytic' is an adjective and must not be used as a noun; editors should also distinguish it from 'comedogenic', its antonym, which describes a substance that promotes comedone formation. The term appears in product claims, ingredient function tables, and clinical protocol rationale sections.
Usage
Usage note: Always use as an adjective modifying a noun (e.g., 'comedolytic agent', 'comedolytic effect'). Distinguish clearly from 'comedogenic' in any document where both appear.
In Context
- "The formulation's comedolytic action was attributed to its 2% salicylic acid content." — Product dossier ingredient rationale
- "The draft copy misused 'comedolytic' as a noun; it should read 'comedolytic agent'." — Copy-editing annotation