Deoxycholic Acid
Pronunciation: dee-ok-see-KOH-lik AS-id
A bile-acid-derived injectable compound that destroys fat cell membranes, used in cosmetic dermatology for non-surgical reduction of submental (double chin) fat.
Full Definition
Deoxycholic acid is a naturally occurring secondary bile acid that, when injected into subcutaneous fat, causes adipocytolysis—the destruction of fat cell membranes—resulting in permanent reduction of localised fat deposits. It is licensed under the brand name Kybella in the United States and Belkyra in several other markets. Cosmetic dermatology editors will encounter this term in treatment summaries, marketing copy, and clinical trials. It should not be confused with hyaluronic acid fillers, which add volume rather than destroy tissue. The compound adjective 'bile-acid-derived' is hyphenated when used as a modifier.
Usage
Usage note: Use the INN 'deoxycholic acid' in clinical and regulatory contexts. Brand names (Kybella, Belkyra) should be capitalised and used only where specifically indicated. Do not confuse with phosphatidylcholine, which is a distinct lipolytic agent.
In Context
- "Two sessions of deoxycholic acid injection resulted in a clinically significant reduction in submental fat at twelve weeks." — Clinical trial report
- "The editor queried whether 'deoxycholic acid' was the approved generic name or whether the brand name Kybella should have been used instead." — Regulatory document review