PLLA
Also written as: PLLA — Poly-L-Lactic Acid
Abbreviation for poly-L-lactic acid, a biodegradable synthetic polymer used as an injectable biostimulator to restore facial volume through collagen synthesis.
Full Definition
Poly-L-lactic acid (PLLA) is the active substance in Sculptra, a biostimulator that, unlike hyaluronic acid fillers, produces gradual volumetric improvement over a treatment series of two to three sessions spaced four to six weeks apart. PLLA microparticles act as a scaffold that provokes a controlled fibroblastic response, increasing dermal collagen density progressively. Regulatory and clinical documents must specify PLLA by its INN or full chemical name on first use; the abbreviation PLLA is then acceptable in subsequent references. Editors should note that 'Sculptra' is a registered trademark and must be capitalised; using it as a generic term for PLLA is an editorial error. Results are described in terms of facial contour restoration rather than immediate line effacement.
Usage
Usage note: Expand on first use as 'poly-L-lactic acid (PLLA)'. Sculptra® is the brand name and must be capitalised with trademark notation in promotional copy.
In Context
- "The article abbreviated poly-L-lactic acid to PLLA without expanding it on first use; the editor inserted the full term in parentheses at first mention." — Peer-reviewed journal manuscript
- "The patient information sheet used 'Sculptra' throughout without once referencing PLLA; the editor recommended adding the generic name for regulatory compliance." — Patient information sheet