LAST
Also written as: LAST — Local Anesthetic Systemic Toxicity
Acronym for local anesthetic systemic toxicity; a medical emergency characterised by CNS and cardiovascular toxicity from excessive plasma local anesthetic levels.
Full Definition
LAST is the established abbreviation in regional and dental anesthesia literature for local anesthetic systemic toxicity. The acronym is used on product safety inserts, emergency protocols, and clinical guidelines from organizations such as ASRA. Editors should be alert to case-sensitivity: 'LAST' (all capitals) is the abbreviation; 'last' in any other casing is the common English adjective/adverb. Because the word 'last' has an ordinary English meaning, editors should confirm contextual meaning when this abbreviation appears without prior expansion in a document.
Usage
Usage note: Must appear in all capitals to distinguish from the common English word 'last.' Expand on first use. Do not use in documents without prior expansion.
In Context
- "The emergency cart contained a lipid rescue kit specifically prepared for LAST management." — Facility emergency preparedness document
- "In the introduction, LAST was expanded correctly as 'local anesthetic systemic toxicity (LAST).'" — Manuscript review comment