Histiocytoma
Pronunciation: /ˌhɪstioʊsaɪˈtoʊmə/
Benign fibrous tumor composed of histiocytes and fibroblasts, synonymous with dermatofibroma in dermatologic contexts.
Full Definition
Histiocytoma is a benign tumor composed of histiocytes (macrophages) and fibroblasts, most commonly occurring in the skin where it is synonymous with dermatofibroma. The lesion typically presents as a firm, brown nodule with characteristic histologic features including spindle cells in a storiform pattern with overlying epidermal hyperplasia. While the term can refer to various histiocytic proliferations throughout the body, in dermatologic surgery it specifically denotes the common benign fibrous tumor of the skin that exhibits the classic 'dimple sign' on physical examination.
Usage
Usage note: In dermatologic contexts, essentially synonymous with dermatofibroma; avoid confusion with malignant histiocytic tumors.
In Context
- "Histologic examination revealed a typical histiocytoma with storiform pattern and no malignant features." — Pathology report
- "The firm nodule on the patient's leg was clinically consistent with a histiocytoma and was excised." — Clinical note