Dermatofibroma
A common benign fibrous nodule of the dermis, most frequently found on the lower limbs, that displays a characteristic dimple sign on lateral compression.
Full Definition
A dermatofibroma is a firm, benign dermal papule or nodule composed of fibroblasts and histiocytes, typically measuring 5–10 mm in diameter. It most commonly appears on the legs of young to middle-aged adults and is characterised by the 'dimple' or 'dimpling' sign—central depression upon lateral pinching—which aids clinical diagnosis. Histologically it shows epidermal hyperplasia overlying a fibrohistiocytic proliferation. Editors should note that dermatofibroma is a single word (no hyphen) and should not be abbreviated in formal documents. Its distinction from dermatofibrosarcoma protuberans is clinically critical and must be accurately reflected in reports.
Usage
Usage note: Do not confuse or abbreviate in ways that could be read as 'DFSP' (dermatofibrosarcoma protuberans), a malignant entity with very different management.
In Context
- "The excision biopsy confirmed a dermatofibroma with clear margins, and no further treatment was required." — Surgical pathology report
- "A solitary dermatofibroma on the left shin was discussed at the minor procedures clinic." — Clinic letter