Keloid
Pronunciation: /ˈkiːlɔɪd/
A fibroproliferative scar that extends beyond the original wound margins, arising from abnormal collagen synthesis.
Full Definition
A keloid is an exuberant, benign fibrous growth resulting from aberrant wound healing, characterised by the excessive deposition of type I and type III collagen that invades tissue beyond the original injury boundary. Unlike hypertrophic scars, keloids do not regress spontaneously and frequently recur after excision. They are more prevalent in individuals with darker Fitzpatrick skin types and commonly affect the earlobes, chest, and upper back. Editors must distinguish 'keloid' from 'hypertrophic scar', as the terms are frequently conflated in lay and semi-clinical writing. Note the spelling: 'keloid', not 'cheloid' (an obsolete variant that occasionally resurfaces).
Usage
Usage note: Do not use 'cheloid'; this spelling is obsolete. Do not conflate with hypertrophic scar, which remains within wound margins.
In Context
- "Post-surgical keloids on the anterior chest wall were treated with a combination of intralesional corticosteroid and silicone sheeting." — Case series treatment description
- "The manuscript used 'keloid' and 'hypertrophic scar' interchangeably; the editor flagged this inconsistency for clinical review." — Substantive editing note