adenosine
Pronunciation: ah-DEN-oh-seen
A naturally occurring nucleoside used to terminate supraventricular tachycardia by temporarily blocking AV conduction.
Full Definition
Adenosine is an endogenous nucleoside that acts on adenosine receptors to cause transient atrioventricular (AV) block, effectively terminating reentrant supraventricular tachycardias (SVT). In emergency cardiology, it is the first-line treatment for stable SVT when vagal maneuvers fail. The medication has an extremely short half-life of less than 10 seconds, requiring rapid intravenous administration followed immediately by saline flush. Common side effects include transient chest discomfort, dyspnea, and flushing. Adenosine is contraindicated in patients with asthma or known hypersensitivity and should be used with caution in patients with heart transplants.
Usage
Usage note: Emphasize rapid administration technique in procedural documentation; note contraindications clearly.
In Context
- "Adenosine 6 mg was given via rapid IV push, successfully terminating the SVT." — Emergency treatment documentation
- "The patient experienced transient chest discomfort following adenosine administration." — Medication administration record