hibernating myocardium
Chronically dysfunctional but viable myocardial tissue with reduced contractility due to chronic ischemia, capable of functional recovery with revascularization.
Full Definition
Hibernating myocardium represents a protective adaptation where chronically ischemic cardiac tissue downregulates its contractile function to match reduced oxygen supply, maintaining cellular viability while appearing akinetic or hypokinetic. Unlike stunned myocardium, hibernating tissue requires ongoing reduced perfusion and will only recover function after successful revascularization. Identification through viability testing (PET, dobutamine stress echo, or delayed-enhancement MRI) is crucial for determining which patients with ischemic cardiomyopathy will benefit from revascularization procedures.
Usage
Usage note: Distinguish from stunned myocardium, which recovers spontaneously without intervention.
In Context
- "PET imaging revealed hibernating myocardium in the anterior wall, supporting candidacy for revascularization." — Nuclear cardiology report
- "The patient's heart failure may improve with PCI if hibernating myocardium is present." — Cardiology consultation