adenoma-to-hyperplasia ratio

Full Definition

The adenoma-to-hyperplasia ratio is a pathological parameter used to evaluate parathyroid tissue specimens, particularly in cases where the distinction between single-gland adenoma and multigland hyperplasia is unclear. This assessment helps determine whether a patient has single-gland disease (adenoma) versus multigland disease (hyperplasia), which has significant implications for surgical management. A higher ratio suggests adenomatous disease, while a lower ratio may indicate hyperplastic changes affecting multiple glands.

Usage

Usage note: Hyphenate the full term. May be abbreviated as A:H ratio in subsequent references.

In Context

• "Pathology revealed an adenoma-to-hyperplasia ratio consistent with single-gland disease." — pathology report
• "The low adenoma-to-hyperplasia ratio suggested possible multigland involvement." — multidisciplinary team meeting note