sestamibi scan
Pronunciation: ses-TAM-ih-bee
Nuclear medicine imaging study using technetium-99m sestamibi to localize abnormal parathyroid tissue.
Full Definition
A sestamibi scan is a specialized nuclear imaging technique that uses technetium-99m sestamibi (Tc-99m MIBI) to identify and localize hyperfunctioning parathyroid glands, particularly adenomas. The radiotracer accumulates in metabolically active tissue, with abnormal parathyroid glands showing delayed washout compared to normal thyroid tissue. This dual-phase imaging protocol is essential for preoperative planning in parathyroid surgery, helping surgeons identify single-gland disease and plan minimally invasive approaches. The scan is particularly valuable when combined with SPECT/CT imaging for precise anatomical localization.
Usage
Usage note: Often shortened to MIBI scan in clinical contexts; sestamibi is the full chemical name.
In Context
- "The sestamibi scan revealed focal uptake in the left inferior parathyroid gland." — radiology report
- "Preoperative sestamibi scanning is recommended for patients undergoing minimally invasive parathyroidectomy." — surgical protocol