Deep brain stimulation
Also written as: DBS — Deep brain stimulation
A neurosurgical procedure involving implanted electrodes that deliver electrical stimulation to specific brain regions for seizure control.
Full Definition
Deep brain stimulation (DBS) for epilepsy involves the surgical implantation of electrodes into specific brain targets, most commonly the anterior thalamic nucleus, to deliver controlled electrical stimulation for seizure reduction. The system consists of implanted leads, an extension cable, and a programmable pulse generator (similar to a cardiac pacemaker) placed under the skin. DBS is considered for patients with pharmacoresistant epilepsy who are not candidates for resective surgery. The SANTE trial demonstrated efficacy of anterior thalamic DBS for focal seizures. Unlike ablative procedures, DBS is reversible and programmable, allowing for optimization of stimulation parameters.
Usage
Usage note: Distinguish from other neurostimulation approaches like VNS and RNS by the intracranial electrode placement.
In Context
- "The patient was evaluated for deep brain stimulation after failing multiple antiseizure medications and resective surgery evaluation." — Surgical consultation note
- "Deep brain stimulation of the anterior thalamic nucleus reduced seizure frequency by 40% at one year follow-up." — Outcome assessment report