Professional
Technical
IVT
twin-to-twin transfusion syndrome
Also written as: TTTS
Serious complication of monochorionic twin pregnancies requiring urgent fetal intervention to prevent perinatal morbidity.
Full Definition
Twin-to-twin transfusion syndrome (TTTS) is a severe complication affecting monochorionic twin pregnancies, characterized by unequal blood flow between twins through placental vascular anastomoses. The donor twin becomes growth-restricted and oligohydramniotic, while the recipient twin develops polyhydramnios and may suffer cardiac overload. Fetoscopic laser photocoagulation of communicating vessels is the preferred treatment for severe cases.
Usage
Usage note: Often abbreviated as TTTS in clinical documentation.
In Context
- "Severe twin-to-twin transfusion syndrome was diagnosed at 18 weeks gestation based on Quintero staging criteria." — Diagnostic report
- "Fetoscopic laser ablation successfully treated the twin-to-twin transfusion syndrome with good outcomes for both twins." — Treatment outcome
Also known as
TTTS
Don't confuse with
twin anemia-polycythemia sequence
selective fetal growth restriction