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Intermediate Technical IVT

Polypharmacy

The concurrent use of multiple medications, typically defined as five or more drugs, common in geriatric cardiology patients.

Full Definition

Polypharmacy refers to the simultaneous use of multiple medications, most commonly defined as five or more prescription drugs, though some definitions use higher thresholds. In geriatric cardiology, polypharmacy is extremely common due to multiple cardiovascular comorbidities requiring treatment. This practice increases risks of drug-drug interactions, adverse effects, medication non-adherence, and prescribing cascades. Clinical editors must be aware that polypharmacy is both a necessary reality and a significant clinical challenge in elderly cardiac patients.

Usage

Usage note: Specify number of medications when possible; distinguish from appropriate multi-drug therapy.

In Context

  • "The patient's polypharmacy regimen included 12 different medications for cardiovascular comorbidities." — Medication reconciliation note
  • "Polypharmacy considerations led to the deprescribing of non-essential medications." — Geriatric cardiology consultation

Also known as

multiple drug therapy concurrent medication use

Contrasted with

monotherapy

Don't confuse with

drug interactions medication adherence

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