acetylcholinesterase inhibitor
Pronunciation: uh-SEE-til-koh-lin-ES-ter-ays
A class of medications that prevent the breakdown of acetylcholine, used to treat cognitive symptoms in dementia.
Full Definition
Acetylcholinesterase inhibitors are pharmaceutical agents that block the enzyme responsible for breaking down acetylcholine in the brain. These medications, including donepezil, rivastigmine, and galantamine, are prescribed to slow cognitive decline in Alzheimer's disease and other dementias. While they do not cure dementia, they may temporarily improve or stabilize cognitive function and daily living abilities. Editors should note that these drugs are often referenced in clinical documentation and care plans for elderly psychiatric patients.
Usage
Usage note: Often abbreviated as ChEI in clinical notes; editors should maintain consistency in usage within documents.
In Context
- "The patient was started on an acetylcholinesterase inhibitor to address progressive memory loss." — Clinical progress note
- "Contraindications for acetylcholinesterase inhibitors include severe hepatic impairment and known hypersensitivity." — Prescribing guideline