cholinesterase inhibitor
Class of medications that block the breakdown of acetylcholine to improve cognitive function in dementia patients.
Full Definition
Cholinesterase inhibitors are a class of medications commonly prescribed for Alzheimer's disease and other dementias. These drugs work by inhibiting the enzyme acetylcholinesterase, which breaks down acetylcholine, a neurotransmitter important for memory and learning. By preventing this breakdown, these medications can temporarily improve or stabilize cognitive symptoms. Common examples include donepezil, rivastigmine, and galantamine. While they do not cure dementia or stop disease progression, they may provide modest symptomatic improvement for some patients.
Usage
Usage note: Note the distinction from anticholinergic medications, which have opposite effects.
In Context
- "The physician initiated a cholinesterase inhibitor to address the patient's mild cognitive decline." — treatment plan
- "Side effects of cholinesterase inhibitors may include nausea, diarrhea, and sleep disturbances." — medication counseling notes