polypharmacy
The concurrent use of multiple medications, particularly problematic in elderly patients due to increased risk of adverse interactions.
Full Definition
Polypharmacy refers to the simultaneous use of multiple medications by a single patient, typically defined as five or more concurrent medications, though some definitions use different thresholds. In geriatric psychiatry, polypharmacy is of particular concern due to age-related changes in drug metabolism, increased sensitivity to side effects, and higher risk of drug-drug interactions. Elderly patients often have multiple chronic conditions requiring various treatments, but polypharmacy can lead to medication cascades, where side effects are treated with additional drugs. Regular medication reviews and deprescribing initiatives are essential components of geriatric psychiatric care.
Usage
Usage note: Single word, no hyphen. Avoid using as a synonym for simple 'multiple medications' without the context of potential problems.
In Context
- "The medication review identified opportunities to reduce polypharmacy-related risks." — Pharmacist consultation report
- "Polypharmacy contributed to the patient's increased fall risk and cognitive symptoms." — Geriatric assessment summary