Intermediate
Technical
In the Industry Vocabulary Test
positive margins
Presence of tumor cells at the edge of surgically removed tissue, indicating incomplete excision.
Full Definition
Positive margins refer to the presence of malignant cells at or within 1-2 mm of the inked surgical margin of a resected specimen, indicating that tumor extends to the edge of the excised tissue. This finding suggests that residual cancer may remain in the patient and is associated with increased risk of local recurrence. In gynecologic oncology, positive margins may necessitate additional surgery, adjuvant radiation therapy, or closer surveillance. The clinical significance varies by tumor type, location, and available treatment options.
Usage
Usage note: Always specify which margin is positive (anterior, posterior, lateral, etc.).
In Context
- "Final pathology revealed positive margins requiring additional treatment planning." — pathology report
- "Re-excision was recommended due to positive margins on the initial specimen." — treatment planning note
Also known as
involved margins
close margins
Contrasted with
negative margins
clear margins
Don't confuse with
close margins
indeterminate margins