gestational trophoblastic disease
Also written as: GTD — Gestational Trophoblastic Disease
Group of disorders arising from placental trophoblast, including molar pregnancies and choriocarcinoma.
Full Definition
Gestational trophoblastic disease (GTD) encompasses a spectrum of disorders originating from placental trophoblastic tissue, ranging from benign hydatidiform moles to malignant choriocarcinoma. These conditions are characterized by abnormal trophoblast proliferation and elevated beta-hCG levels. Complete and partial molar pregnancies represent the most common forms, while persistent GTD may develop into invasive mole or choriocarcinoma requiring chemotherapy. Diagnosis relies on histopathology, imaging, and serial beta-hCG monitoring.
Usage
Usage note: Always specify subtype when known; emphasize need for long-term beta-hCG monitoring.
In Context
- "The pathology confirmed gestational trophoblastic disease requiring immediate beta-hCG monitoring." — Pathology consultation
- "Serial beta-hCG levels will guide management of this case of gestational trophoblastic disease." — Follow-up plan