vulvar lichen sclerosus
Pronunciation: LYE-ken skler-OH-sus
A chronic inflammatory skin condition affecting the vulva, characterized by white, atrophic patches and intense itching.
Full Definition
Vulvar lichen sclerosus is a chronic, progressive inflammatory dermatosis that primarily affects the anogenital region in women. The condition is characterized by white, porcelain-like patches of thin, atrophic skin that may develop fissures, erosions, or scarring. Patients typically experience severe pruritus, burning, dyspareunia, and pain. The exact etiology is unknown but may involve autoimmune factors and hormonal influences. If left untreated, lichen sclerosus can lead to architectural changes of the vulva, including resorption of the labia minora and clitoral hood, and narrowing of the vaginal introitus. There is also a small risk of malignant transformation to squamous cell carcinoma, making long-term follow-up essential.
Usage
Usage note: Preferred term over older designation 'lichen sclerosus et atrophicus'; requires long-term monitoring.
In Context
- "Biopsy confirmed vulvar lichen sclerosus with characteristic dermal sclerosis and inflammatory infiltrate." — Pathology report
- "The patient responded well to topical clobetasol for treatment of vulvar lichen sclerosus." — Follow-up visit note