Intermediate
Technical
IVT
close surgical margin
Tumor clearance of less than 5mm from the edge of resected tissue.
Full Definition
A close surgical margin indicates tumor cells within 1-5mm of the resection edge, representing suboptimal but potentially adequate clearance. This finding increases local recurrence risk and often prompts consideration of adjuvant radiation therapy. Close margins must be distinguished from positive margins (tumor at the edge) and adequate margins (≥5mm clearance). The clinical significance varies by anatomic site and tumor characteristics, requiring multidisciplinary discussion for treatment planning.
Usage
Usage note: Specify the margin distance when possible; distinguish from positive margins.
In Context
- "The pathology report showed close surgical margins at the deep and lateral aspects." — pathology report
- "Close surgical margins prompted recommendation for adjuvant radiation therapy." — treatment planning conference
Also known as
narrow margin
marginal clearance
Contrasted with
wide margin
positive margin
Don't confuse with
positive margin
inadequate margin