mucositis
Pronunciation: myoo-koh-SY-tis
Inflammatory reaction of mucous membranes commonly occurring during head and neck radiation therapy.
Full Definition
Mucositis is an inflammatory reaction affecting the mucous membranes of the oral cavity, oropharynx, and other mucosal surfaces exposed to radiation therapy or chemotherapy. In head and neck cancer patients, oral mucositis is a nearly universal acute side effect of radiation therapy, characterized by erythema, ulceration, and severe pain that can limit oral intake and require treatment breaks. The condition typically develops during the second to third week of radiation therapy and may persist for several weeks after treatment completion. Management includes pain control, nutritional support, and prophylactic measures to prevent secondary infections.
Usage
Usage note: Grade severity using CTCAE criteria; distinguish from infectious causes.
In Context
- "Grade 3 mucositis developed during week 4 of radiation, requiring a treatment break and PEG tube feeding." — Treatment note
- "Prophylactic oral care protocols aim to minimize the severity of radiation-induced mucositis." — Care protocol