Binet staging
Pronunciation: bee-NAY staging
A staging system for chronic lymphocytic leukemia based on the number of lymphoid areas involved and presence of anemia or thrombocytopenia.
Full Definition
The Binet staging system is a European prognostic classification for chronic lymphocytic leukemia that divides patients into three stages (A, B, C) based on the number of enlarged lymphoid areas and the presence of cytopenias. Stage A involves fewer than three lymphoid areas, Stage B involves three or more areas, and Stage C indicates anemia or thrombocytopenia. This system helps predict prognosis and guide treatment decisions in CLL patients.
Usage
Usage note: Always capitalize 'Binet' as it is named after French hematologist Jacques Binet.
In Context
- "The patient was classified as Binet stage B due to involvement of bilateral cervical, axillary, and inguinal lymph nodes." — Clinical assessment report
- "Binet staging remains an important prognostic tool in European centers for CLL evaluation." — Hematology review article