remission
The absence or significant reduction of cancer signs and symptoms, classified as complete or partial based on specific criteria.
Full Definition
Remission in hematologic oncology refers to the absence or significant reduction of disease signs and symptoms following treatment. Complete remission (CR) is defined by specific criteria including normal blood counts, less than 5% blasts in bone marrow, and absence of extramedullary disease. Partial remission (PR) involves significant improvement but not complete normalization of disease parameters. Molecular remission indicates undetectable disease by sensitive molecular techniques. The concept of remission is crucial for treatment planning and prognosis, though it does not necessarily indicate cure.
Usage
Usage note: Distinguish between complete remission (CR), partial remission (PR), and molecular remission; not synonymous with cure.
In Context
- "The patient achieved complete remission after four cycles of induction therapy." — Treatment response assessment
- "Molecular remission was confirmed by undetectable BCR-ABL transcripts." — Follow-up laboratory report