Intermediate
Technical
In the Industry Vocabulary Test
Estradiol
Pronunciation: es-tra-DYE-all
The most potent naturally occurring estrogen hormone, essential for reproductive function assessment.
Full Definition
Estradiol (E2) is the primary and most biologically active form of estrogen produced mainly by the ovaries in premenopausal women. It plays crucial roles in menstrual cycle regulation, fertility, and bone health. Estradiol levels are measured to evaluate ovarian function, diagnose menopause, monitor hormone replacement therapy, and assess fertility treatments. In pediatric patients, elevated levels may indicate precocious puberty.
Usage
Usage note: Distinguish from other estrogens; specify measurement units (pg/mL or pmol/L).
In Context
- "Estradiol levels below 30 pg/mL confirm postmenopausal status." — Endocrinology report
- "Serial estradiol monitoring is required during IVF stimulation cycles." — Fertility clinic protocol
Also known as
E2
17β-estradiol
Don't confuse with
Estrone
Estriol
Testosterone