Salivary Cortisol Collection
A non-invasive sampling method for measuring free cortisol levels using specialized collection tubes.
Full Definition
Salivary cortisol collection is a patient-friendly sampling technique that measures the biologically active, unbound fraction of cortisol in saliva. This method eliminates the stress-induced cortisol elevation that can occur with blood draws and provides a more accurate representation of tissue cortisol levels. Collection requires specific timing protocols, often multiple samples throughout the day, and specialized saliva collection tubes. The method is particularly valuable for circadian rhythm assessment and cortisol awakening response testing. Proper patient preparation is crucial, including restrictions on eating, drinking, and oral hygiene before collection.
Usage
Usage note: Always specify collection method when discussing cortisol testing to avoid confusion with other sample types.
In Context
- "The patient instructions emphasized proper timing for salivary cortisol collection at awakening." — Patient preparation sheet
- "Salivary cortisol collection offers advantages over serum testing for outpatient monitoring." — Clinical protocol guideline