Total Testosterone
Laboratory measurement of both bound and free testosterone in serum, representing the complete hormonal picture.
Full Definition
Total testosterone measures all testosterone in the blood sample, including hormone bound to proteins and the small fraction that is freely circulating. This test is often the initial screening tool for testosterone deficiency or excess, though it may not reflect the biologically active hormone levels. In clinical contexts, editors should note that 'total testosterone' is distinct from 'free testosterone' and that reference ranges vary significantly between laboratories and patient populations.
Usage
Usage note: Always specify 'total' when distinguishing from free or bioavailable testosterone measurements.
In Context
- "The patient's total testosterone level was within normal limits at 450 ng/dL." — Laboratory report
- "Total testosterone measurements should be collected in the morning due to circadian variation." — Clinical guideline