DAPT
Dual antiplatelet therapy combining aspirin with a P2Y12 inhibitor, essential for preventing stent thrombosis after PCI.
Full Definition
Dual antiplatelet therapy (DAPT) represents the cornerstone of pharmacological management following percutaneous coronary intervention with stent placement. The regimen typically combines aspirin with a P2Y12 receptor antagonist such as clopidogrel, prasugrel, or ticagrelor. DAPT duration depends on multiple factors including stent type, indication for PCI, bleeding risk, and ischemic risk. Current guidelines recommend a minimum of one month for bare metal stents and 6-12 months for drug-eluting stents, though duration may be shortened or extended based on individual patient assessment using validated risk scores.
Usage
Usage note: Always specify the component medications when documenting DAPT.
In Context
- "DAPT duration was extended to 30 months based on high ischemic risk and acceptable bleeding profile." — Discharge medication reconciliation
- "The DAPT score of 3 supported continuation beyond the standard 12-month period." — Cardiology follow-up note