ischemic time
The duration from symptom onset to restoration of coronary blood flow, a critical metric in acute coronary syndrome management.
Full Definition
Ischemic time represents the total duration of myocardial ischemia from symptom onset until successful reperfusion is achieved through percutaneous coronary intervention. This metric is crucial in acute coronary syndromes, particularly STEMI, where prolonged ischemic time correlates with larger infarct size, reduced left ventricular function, and worse clinical outcomes. Current guidelines emphasize minimizing total ischemic time through system-based approaches including pre-hospital diagnosis, direct catheterization laboratory activation, and streamlined in-hospital processes. Total ischemic time includes pre-hospital delay, door-to-balloon time, and any procedural delays.
Usage
Usage note: Distinguish from door-to-balloon time, which is only one component of total ischemic time.
In Context
- "Total ischemic time was 180 minutes from symptom onset to vessel reopening." — Quality metrics reporting
- "Minimizing ischemic time remained the primary goal despite transfer delays." — Case management