absent end-diastolic flow
Also written as: AEDF — Absent End-Diastolic Flow
Doppler ultrasound finding in umbilical artery showing no forward blood flow during diastole, indicating severe placental compromise.
Full Definition
Absent end-diastolic flow (AEDF) is a Doppler ultrasound finding in the umbilical artery characterized by the complete absence of forward blood flow during the diastolic phase of the cardiac cycle. This finding indicates severe placental vascular compromise and increased placental resistance. AEDF is associated with significant risk of fetal growth restriction, fetal hypoxia, and adverse perinatal outcomes, often necessitating close monitoring and potential delivery.
Usage
Usage note: AEDF is more severe than decreased flow but less severe than reversed flow.
In Context
- "Umbilical artery Doppler studies demonstrated absent end-diastolic flow at 28 weeks gestation." — Ultrasound report
- "The development of AEDF prompted daily fetal surveillance and delivery planning." — Clinical management note