HELLP syndrome
Pronunciation: HEL-ip
Also written as: HELLP — Hemolysis, Elevated Liver enzymes, Low Platelet count
A severe pregnancy complication characterized by hemolysis, elevated liver enzymes, and low platelet count.
Full Definition
HELLP syndrome is a life-threatening obstetric emergency representing a variant or complication of preeclampsia. The acronym describes three key laboratory findings: Hemolysis (breakdown of red blood cells), Elevated Liver enzymes (indicating hepatic dysfunction), and Low Platelet count (thrombocytopenia). This condition typically occurs in the third trimester or immediately postpartum, presenting with right upper quadrant pain, nausea, vomiting, and malaise. HELLP syndrome requires immediate medical intervention, often including corticosteroids for fetal lung maturity and prompt delivery. The condition can occur without typical preeclampsia symptoms, making recognition challenging.
Usage
Usage note: All capitals for the acronym; ensure all three components are present for diagnosis.
In Context
- "Laboratory results confirmed HELLP syndrome with platelets of 85,000 and AST of 180." — Emergency department evaluation
- "The patient developed postpartum HELLP syndrome requiring intensive monitoring." — Postpartum care documentation