Acneiform Eruption
Pronunciation: ak-NEE-ih-form ih-RUP-shun
A skin reaction that resembles acne vulgaris but is caused by an external agent such as a drug, chemical, or systemic condition rather than by follicular pathology.
Full Definition
An acneiform eruption is a drug- or chemical-induced skin reaction characterised by papules and pustules that closely mimic acne vulgaris. Unlike true acne, acneiform eruptions typically lack comedones and may appear suddenly in an unusual distribution, such as the trunk or upper arms. Common culprits include corticosteroids, lithium, halogens, and targeted cancer therapies (e.g., EGFR inhibitors). Editors must distinguish this term from 'acne vulgaris' and avoid conflating the two in clinical case reports or product labeling. Accurate use is critical in adverse-event documentation and pharmacovigilance reports.
Usage
Usage note: Do not use 'acneiform' and 'acne' interchangeably; the former implies a secondary, reactive process rather than primary acne pathology.
In Context
- "The patient developed an acneiform eruption on the chest and shoulders within two weeks of starting systemic corticosteroid therapy." — Clinical case report
- "Authors should specify whether the reaction constitutes acne vulgaris or an acneiform eruption, as the distinction affects treatment recommendations." — Editorial style guide note