Intermediate
Technical
IVT
cytotoxic
Describes agents or treatments that are toxic to cells, particularly cancer cells.
Full Definition
Cytotoxic refers to substances or treatments that damage or destroy cells, particularly rapidly dividing cells such as cancer cells. In oncology, cytotoxic chemotherapy works by interfering with cell division and DNA replication, leading to cell death. While these agents preferentially target cancer cells due to their rapid growth, they can also affect normal rapidly dividing cells, such as those in bone marrow, hair follicles, and the gastrointestinal tract, leading to characteristic side effects.
Usage
Usage note: Often confused with cytostatic, which stops cell division without necessarily killing cells.
In Context
- "The cytotoxic effects of doxorubicin require careful cardiac monitoring." — Safety protocol document
- "Cytotoxic chemotherapy remains the backbone of treatment for aggressive lymphomas." — Treatment guideline
Also known as
cell-killing
cell-toxic
Contrasted with
cytoprotective
Don't confuse with
cytostatic