hyperbilirubinemia
Pronunciation: HY-per-bil-ee-roo-bin-EE-mee-ah
An elevated level of bilirubin in the blood, commonly causing jaundice in newborns.
Full Definition
Hyperbilirubinemia refers to an abnormally high concentration of bilirubin in the blood, typically manifesting as jaundice (yellowing of the skin and eyes) in newborns. This condition is particularly common in the first week of life and can be physiological (normal) or pathological (requiring treatment). Severe hyperbilirubinemia can lead to kernicterus, a serious neurological complication. Treatment options include phototherapy, exchange transfusion, and addressing underlying causes such as hemolysis or metabolic disorders.
Usage
Usage note: Distinguish between conjugated and unconjugated hyperbilirubinemia in clinical documentation.
In Context
- "The newborn developed significant hyperbilirubinemia requiring intensive phototherapy." — Treatment plan
- "Monitoring for hyperbilirubinemia is essential in all newborns during the first 72 hours of life." — Nursing protocol