retinopathy of prematurity
An eye disease affecting premature infants characterized by abnormal blood vessel development in the retina.
Full Definition
A potentially blinding eye disease that affects premature infants, particularly those born before 31 weeks gestation or weighing less than 1,250 grams at birth. ROP occurs when normal blood vessel development in the retina is disrupted, leading to abnormal vessel growth that can cause retinal scarring and detachment. The disease is staged from 1 to 5 based on severity, with higher stages requiring immediate intervention to prevent blindness. Risk factors include extreme prematurity, prolonged oxygen exposure, and various medical complications. Regular ophthalmologic screening is essential for all at-risk infants to enable timely treatment.
Usage
Usage note: Commonly abbreviated as ROP; staging system should be specified in clinical documentation.
In Context
- "Ophthalmologic examination revealed Stage 3 retinopathy of prematurity requiring laser photocoagulation therapy." — Ophthalmology consultation
- "All infants born at less than 30 weeks gestation require serial retinopathy of prematurity screening examinations." — Clinical guideline