anisocoria
Pronunciation: an-eye-so-KOR-ee-ah
Unequal pupil size that may be physiological or indicate neurological pathology affecting pupillary innervation.
Full Definition
Anisocoria refers to a difference in pupil size between the two eyes, which can be physiological or pathological. In neuro-ophthalmology, pathological anisocoria may indicate Horner syndrome (smaller pupil), third nerve palsy (larger pupil), Adie's tonic pupil, or pharmacological effects. The key to evaluation is determining which pupil is abnormal by observing the anisocoria in both bright and dim illumination. Physiological anisocoria is common and benign, typically measuring less than 1mm difference and remaining constant in different lighting conditions.
Usage
Usage note: Document the degree of anisocoria and note whether it varies with lighting conditions to aid in diagnosis.
In Context
- "The patient demonstrated 2mm of anisocoria that was more pronounced in dim lighting, suggesting Horner syndrome." — Physical examination findings
- "Pharmacological testing was performed to determine the cause of the acquired anisocoria." — Diagnostic workup