choroid plexus papilloma
A benign intraventricular tumor arising from choroid plexus epithelium, characterized by papillary architecture.
Full Definition
Choroid plexus papilloma is a benign, WHO grade I tumor that arises from the choroid plexus epithelium within the ventricular system. These tumors maintain the normal papillary architecture of choroid plexus with a single layer of cuboidal to columnar epithelium overlying a vascular connective tissue core. They most commonly occur in the lateral ventricles in children and the fourth ventricle in adults. The tumor cells are typically ciliated and may produce cerebrospinal fluid, potentially leading to hydrocephalus. The epithelium shows uniform polarity and lacks significant mitotic activity or pleomorphism.
Usage
Usage note: Benign counterpart to choroid plexus carcinoma; architecture and mitotic activity are key distinguishing features.
In Context
- "The intraventricular mass showed papillary architecture with single-layered epithelium characteristic of choroid plexus papilloma." — Neuropathology report
- "Hydrocephalus secondary to choroid plexus papilloma was managed with tumor resection and CSF diversion." — Neurosurgical case note