gross total resection
Also written as: GTR — gross total resection
Complete surgical removal of a visible tumor with no residual mass apparent on imaging.
Full Definition
Gross total resection (GTR) refers to the complete surgical removal of a brain tumor where no visible tumor tissue remains on postoperative imaging studies, typically high-resolution MRI. This represents the most extensive surgical debulking possible while preserving neurological function, and is generally associated with improved patient outcomes and longer survival times, particularly for malignant tumors. However, GTR does not guarantee that microscopic tumor cells have not been left behind, as imaging resolution cannot detect cellular-level disease. The achievement of GTR depends on factors including tumor location, proximity to eloquent brain areas, tumor consistency, and the patient's overall condition.
Usage
Usage note: Commonly abbreviated as GTR; distinguish from cure, as microscopic disease may remain.
In Context
- "Gross total resection was achieved with preservation of motor function." — operative summary
- "Postoperative MRI confirmed gross total resection of the frontal mass." — imaging report