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Intermediate Technical IVT

bouton

Pronunciation: boo-TOHN

Swollen terminal or en passant enlargement of an axon containing synaptic vesicles.

Full Definition

A bouton is a specialized axonal enlargement that serves as a presynaptic terminal or intermediate swelling along an axon. These structures contain high concentrations of synaptic vesicles, mitochondria, and release machinery necessary for neurotransmission. Boutons can be terminal (at axon endings) or en passant (along the axon shaft), and their morphology varies significantly across different neuron types and brain regions.

Usage

Usage note: From French 'button' - maintain italicization in some style guides when used as borrowed terminology.

In Context

  • "Large mossy fiber boutons formed complex synapses with CA3 pyramidal neurons." — Hippocampal connectivity study
  • "En passant boutons were identified along the entire length of the GABAergic axon." — Interneuron morphology paper

Also known as

synaptic bouton terminal bouton axon terminal

Don't confuse with

varicosity growth cone

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